TNFRSF25 Polyclonal Antibody for Human(Homo sapiens) | EIAab.comTNFRSF25 Polyclonal Antibody for Human(Homo sapiens) | EIAab.com

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TNFRSF25 (Gene name),

Tumor necrosis factor receptor superfamily member 25 (Protein name ), TNR25_HUMAN from NCBI database.

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General Annotation

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Antigen Annotation

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3D

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Predicted Eptitope

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Vaild Sequence

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Gene name:

TNFRSF25(UNQ455/PRO779;APO3;DDR3;DR3;TNFRSF12;WSL;WSL1);

Protein name:

Tumor necrosis factor receptor superfamily member 25;

Alternative:

Apoptosis-inducing receptor AIR;Apo-3;Apoptosis-mediating receptor TRAMP;Apoptosis-mediating receptor DR3;Lymphocyte-associated receptor of death(LARD);Death receptor 3;Protein WSL-1;Protein WSL;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Homodimer. Interacts strongly via the death domains with TNFRSF1 and TRADD to activate at least two distinct signaling cascades, apoptosis and NF-kappa-B signaling. Interacts with BAG4.

Function:

Receptor for TNFSF12/APO3L/TWEAK. Interacts directly with the adapter TRADD. Mediates activation of NF-kappa-B and induces apoptosis. May play a role in regulating lymphocyte homeostasis.

Subcellular Location:

Isoform 12 Secreted

Protein Attributes:

Sequence length:

417

Sequence:

50:

MEQRPRGCAA | VAAALLLVLL | GARAQGGTRS | PRCDCAGDFH | KKIGLFCCRG |

100:

CPAGHYLKAP | CTEPCGNSTC | LVCPQDTFLA | WENHHNSECA | RCQACDEQAS |

150:

QVALENCSAV | ADTRCGCKPG | WFVECQVSQC | VSSSPFYCQP | CLDCGALHRH |

200:

TRLLCSRRDT | DCGTCLPGFY | EHGDGCVSCP | TSTLGSCPER | CAAVCGWRQM |

250:

FWVQVLLAGL | VVPLLLGATL | TYTYRHCWPH | KPLVTADEAG | MEALTPPPAT |

300:

HLSPLDSAHT | LLAPPDSSEK | ICTVQLVGNS | WTPGYPETQE | ALCPQVTWSW |

350:

DQLPSRALGP | AAAPTLSPES | PAGSPAMMLQ | PGPQLYDVMD | AVPARRWKEF |

400:

VRTLGLREAE | IEAVEVEIGR | FRDQQYEMLK | RWRQQQPAGL | GAVYAALERM |

417:

GLDGCVEDLR | SRLQRGP

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

UniGene:

KEGG:

SMR:

Pfam:

String:

MIM:

Uniprot:

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ELISA Kit for Human Tumor necrosis factor receptor superfamily member 25

Cat.:

E10630h

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MSDS:

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Packing:

96T

CLIA Kit for Human Tumor necrosis factor receptor superfamily member 25

Cat.:

U10630h

Price:

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MSDS:

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Packing:

96T

Polyclonal Antibody for Human Tumor necrosis factor receptor superfamily member 25

Cat.:

P10630Rb-h

Price:

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Packing:

40ug/0.2ml

Monoclonal Antibody for Human Tumor necrosis factor receptor superfamily member 25

Protein for Human Tumor necrosis factor receptor superfamily member 25

R&D Technical Data

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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

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Precision

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Recovery

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Linearity

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References

1.

"A death-domain-containing receptor that mediates apoptosis."
Kitson J. , Raven T. , Jiang Y.-P. , Goeddel D.V. , Giles K.M. , Pun K.-T. , Grinham C.J. , Brown R. , Farrow S.N.
Nature384:372-375(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1; 3 AND 4);MUTAGENESIS
tissue: Lymphoid tissue.
2.

"Signal transduction by DR3, a death domain-containing receptor related to TNFR-1 and CD95."
Chinnaiyan A.M. , O'Rourke K. , Yu G.-L. , Lyons R.H. , Garg M. , Duan D.R. , Xing L. , Gentz R. , Ni J. , Dixit V.M.
Science274:990-992(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
tissue: Umbilical vein endothelial cell.
3.

Degli-Esposti M.A. , Din W.S. , Cosman D. , Smith C.A. , Goodwin R.G.
Submitted (1997-01) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
4.

"Apo-3, a new member of the tumor necrosis factor receptor family, contains a death domain and activates apoptosis and NF-kappa-B."
Marsters S.A. , Sheridan J.P. , Donahue C.J. , Pitti R.M. , Gray C.L. , Goddard A.D. , Bauer K.D. , Ashkenazi A.
Curr. Biol.6:1669-1676(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
tissue: Heart.
5.

"LARD: a new lymphoid-specific death domain containing receptor regulated by alternative pre-mRNA splicing."
Screaton G.R. , Xu X.-N. , Olsen A.L. , Cowper A.E. , Tan R. , McMichael A.J. , Bell J.I.
Proc. Natl. Acad. Sci. U.S.A.94:4615-4619(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1; 2; 3; 4; 5; 6; 7; 8; 9 AND 10)
6.

"A new death receptor 3 isoform: expression in human lymphoid cell lines and non-Hodgkin's lymphomas."
Warzocha K. , Ribeiro P. , Charlot C. , Renard N. , Coiffier B. , Salles G.
Biochem. Biophys. Res. Commun.242:376-379(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 11 AND 12)
7.

Shiozawa S. , Konishi Y. , Murayama K. , Mukae N. , Yamamoto E. , Hayashi S. , Sato M. , Shiozawa K. , Tsukamoto Y.
Submitted (2000-11) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] (ISOFORM 1);VARIANT GLY-159
8.

"The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment."
Clark H.F. , Gurney A.L. , Abaya E. , Baker K. , Baldwin D.T. , Brush J. , Chen J. , Chow B. , Chui C. , Crowley C. , Currell B. , Deuel B. , Dowd P. , Eaton D. , Foster J.S. , Grimaldi C. , Gu Q. , Hass P.E. , more...
Genome Res.13:2265-2270(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
9.

NIEHS SNPs program
Submitted (2003-03) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANTS GLN-23; GLY-159 AND ARG-254
10.

"The DNA sequence and biological annotation of human chromosome 1."
Gregory S.G. , Barlow K.F. , McLay K.E. , Kaul R. , Swarbreck D. , Dunham A. , Scott C.E. , Howe K.L. , Woodfine K. , Spencer C.C.A. , Jones M.C. , Gillson C. , Searle S. , Zhou Y. , Kokocinski F. , McDonald L. , Evans R. , Phillips K. , more...
Nature441:315-321(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
11.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 10)
tissue: Brain.
12.

"TRAMP, a novel apoptosis-mediating receptor with sequence homology to tumor necrosis factor receptor 1 and Fas(Apo-1/CD95)."
Bodmer J.-L. , Burns K. , Schneider P. , Hofmann K. , Steiner V. , Thome M. , Bornand T. , Hahne M. , Schroeter M. , Wilson A. , French L.E. , Browning J.L. , Macdonald H.R. , Tschopp J.
Immunity6:79-88(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 4-417
tissue: Brain.
tissue: Fetal lung.
13.

Chaudhary P.M. , Hood L.E.
Submitted (1997-01) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA] OF 7-417
tissue: Brain.
14.

"Prevention of constitutive TNF receptor 1 signaling by silencer of death domains."
Jiang Y. , Woronicz J.D. , Liu W. , Goeddel D.V.
Science283:543-546(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH BAG4
15.

"An unappreciated role for RNA surveillance."
Hillman R.T. , Green R.E. , Brenner S.E.
Genome Biol.5:R8.1-R8.16(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SPLICE ISOFORM(S) THAT ARE POTENTIAL NMD TARGET(S)

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